Anxious Stomachs, Anxious Minds: Understanding the Link Between Gut Health and Anxiety

April 10, 2024
Gut Health

In recent years, there has been a growing interest in the connection between mental health and the gut. The intricate relationship between anxiety and gut health has emerged as a fascinating area of study, shedding light on the profound influence our digestive system can have on our emotional well-being. While traditionally viewed as separate entities, emerging research suggests that the gut and brain are intricately connected, with disturbances in one often affecting the other. In this blog post, we delve into the correlation between anxiety and gut health, exploring the mechanisms behind this relationship and discussing naturopathic interventions to support mental health through gut health support. 

The Gut-Brain Axis:

At the heart of the correlation between anxiety and gut health lies the gut-brain axis, a complex communication network that links the central nervous system with the enteric nervous system, which governs the function of the gastrointestinal tract. This bidirectional pathway allows for constant communication between the gut and the brain, influencing various physiological processes, including digestion, mood, and cognition.

Role of the Microbiome:

Central to the gut-brain axis is the gut microbiome, a diverse ecosystem of trillions of microorganisms residing in the gastrointestinal tract. These microorganisms play a crucial role in maintaining gut health and modulating immune function. Moreover, they produce neurotransmitters and metabolites that can directly influence brain function and behavior.

Research indicates that alterations in the composition and diversity of the gut microbiome, known as dysbiosis, may contribute to the development of anxiety disorders. Studies have shown that individuals with anxiety disorders often exhibit differences in their gut microbiota compared to healthy controls. Furthermore, experimental manipulations of the microbiome in animal models have been shown to affect anxiety-like behavior, suggesting a causal relationship between gut dysbiosis and anxiety. (1) 

Communication Pathways:

The gut communicates with the brain through various pathways, including the vagus nerve, immune system signaling, and the production of microbial metabolites. For instance, certain gut bacteria produce neurotransmitters such as serotonin and gamma-aminobutyric acid (GABA), which play key roles in regulating mood and anxiety. Additionally, gut-derived inflammatory signals can activate the brain’s immune response, influencing mood and behavior.

Moreover, the gut microbiome interacts with the hypothalamic-pituitary-adrenal (HPA) axis, a key regulator of the body’s stress response. Dysregulation of the HPA axis is commonly observed in individuals with anxiety disorders, and emerging evidence suggests that the gut microbiome may modulate HPA axis activity, thereby influencing susceptibility to stress and anxiety.


  1. Eat a Balanced Diet: Incorporate a variety of fruits, vegetables, whole grains, lean proteins, and healthy fats into your meals. These foods provide essential nutrients and fiber that support a healthy gut microbiome.
  2. Include Fermented Foods: Fermented foods like yogurt, kefir, sauerkraut, kimchi, and kombucha are rich in beneficial probiotics that promote gut health. Incorporating these foods into your diet can help maintain a diverse and thriving microbiome.
  3. Limit Processed Foods and Sugars: High-sugar and processed foods can disrupt the balance of bacteria in your gut and contribute to inflammation. Limiting your intake of these foods can support a healthier gut environment.
  4. Stay Hydrated: Drinking plenty of water is essential for maintaining optimal digestive function. Aim to drink at least 8 glasses of water per day to keep your digestive system hydrated and functioning properly.
  5. Manage Stress: Chronic stress can negatively impact gut health and contribute to digestive issues. Practice stress-reduction techniques such as mindfulness, meditation, deep breathing exercises, yoga, or spending time in nature to help manage stress levels.
  6. Get Adequate Sleep: Quality sleep is crucial for gut health and overall well-being. Aim for 7-9 hours of uninterrupted sleep per night to support healthy digestion and mood regulation.
  7. Exercise Regularly: Regular physical activity can improve gut motility and promote a diverse microbiome. Aim for at least 30 minutes of moderate exercise most days of the week to support your gut health and mood.
  8. Limit Antibiotic Use: Antibiotics can disrupt the balance of bacteria in your gut, leading to dysbiosis. Only use antibiotics when necessary and work with your healthcare provider to explore alternatives when possible.
  9. Consider Probiotic Supplements: If you’re not able to get enough probiotics from food alone, consider taking a high-quality probiotic supplement to support your gut health. 


The correlation between anxiety and gut health highlights the intricate interplay between the gut microbiome and the brain. Emerging research suggests that disruptions in gut microbial composition and function may contribute to the development and exacerbation of anxiety disorders. Understanding how the gut and brain are connected gives us new ways to help people with anxiety. By exploring natural approaches alongside traditional treatments, we can find even more ways to support mental health.

If you’re experiencing persistent digestive issues or mood disturbances, consider consulting with one of our naturopathic doctors HERE.


  1. Cryan, J. F., O’Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., Guzzetta, K. E., Jaggar, M., Long-Smith, C. M., Lyte, J. M., Martin, J. A., Molinero-Perez, A., Moloney, G., Morelli, E., Morillas, E., O’Connor, R., Cruz-Pereira, J. S., Peterson, V. L., Rea, K., Ritz, N. L., Sherwin, E., Spichak, S., Teichman, E. M., van de Wouw, M., Ventura-Silva, A. P., Wallace-Fitzsimons, S. E., Hyland, N., Clarke, G., & Dinan, T. G. (2019). The Microbiota-Gut-Brain Axis. Physiological Reviews, 99(4), 1877–2013.

Written by: Dr. My Tang, N.D

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